​Renowned for her rich blend of soul, R&B, and Latin influences, Manuela is a powerhouse vocalist, singer,songwriter/composer/producer, band-leader & multi instrumentalist.

She performed her own original songs alongside Chaka Khan, George Duke, Carleen Anderson, Xantone Blacq, Gino Vannelli, Angie Stone, Joss Stone.

In 2000 she was signed by Sony Publishing UK.

She worked as a backing vocalist for a list of international superstars that includes John Legend,  R Kelly, Amy Winehouse, Black Eye Peas, Chic, Joselyn Brown, Will Smith, Blu Cantrel, Sean Paul, Wyclef Jean, Shalamar, Lionel Richie, Beverly Knight, Kele Le Roc, Omar, Kym Mazelle, Tom Jones, Westlife, Blue, Lee Ryan, Vanessa Haynes, Andrew Roachford, Boy George and the Culture Club, Kym Mazelle, Angie Brown, Carleen Anderson, Mary Pearce, Kele Le Roc, Mario Biondi, Izzy Dunn and the London Community Gospel Choir, Cece Rogers and Gianna Nannini.

Other collaborations include Steven Tibet, Gianluca Mosole, Andrea T Mendoza and Britalics.